Ivanović's mother Dragana, who is a lawyer, attends all of her daughter's matches. Her father, Miroslav, a self-employed businessman, attends as many events as he possibly can. Ana has a younger brother, Miloš, with whom she loves to play basketball.
Ivanović confirmed in November 2008 that she was romantically involved with Spanish tennis player Fernando Verdasco; however, it was reported that the relationship ended in January 2009. Some of her best friends include close childhood family friend Novak Djokovic, whom she has known since she was 5 years old, and current world number 1 Rafael Nadal. She admires former No.1 tennis player Roger Federer.